Phosphatidylserine (PS)
The Brain Cell Membrane Nutrient
Phosphatidylserine is a phospholipid that forms a critical component of cell membranes, particularly in the brain where it makes up about 15% of the phospholipid pool. It's essential for neuronal signaling, neurotransmitter release, and cognitive function. PS levels decline with age, making supplementation valuable for maintaining brain health.

Per Chew
5 mg
Discover how Phosphatidylserine supports your dog's health and longevity
Maintains the structural integrity and fluidity of neuronal membranes, essential for proper brain cell function.
Supports memory formation, learning ability, and cognitive flexibility by enabling proper neuronal signaling.
Facilitates the release of key neurotransmitters including acetylcholine, dopamine, and serotonin.
Helps modulate cortisol response to stress, supporting balanced reactions to challenging situations.
Watch this short animation to understand how Phosphatidylserine supports your dog's health at the cellular level

Scientific animation showing the mechanism of action of Phosphatidylserine (PS)
Phosphatidylserine is incorporated into neuronal cell membranes where it maintains membrane fluidity and supports the function of membrane-bound proteins. This enables proper neurotransmitter release, receptor function, and cell-to-cell communication. PS also supports glucose uptake into brain cells, ensuring neurons have the energy they need. Additionally, PS helps modulate the cortisol stress response.
Timing: Can be given any time of day
Cognitive benefits develop gradually over 4-12 weeks of consistent use.
Phosphatidylserine has an excellent safety profile with extensive research in both animals and humans. It's a natural component of cell membranes and is found in foods like soybeans and egg yolks. No significant adverse effects have been reported at supplemental doses.
Scientific studies supporting the benefits of Phosphatidylserine
Crook TH, Tinklenberg J, Yesavage J, et al.
Neurology, 1991
Clinical trial demonstrating PS improved memory in subjects with age-related cognitive decline.
Glade MJ, Smith K
Nutrition, 2015
Comprehensive review of PS's role in brain function and cognitive health.
View StudyKato-Kataoka A, Sakai M, Ebina R, et al.
Journal of Clinical Biochemistry and Nutrition, 2010
Showed PS supplementation improved memory and cognitive function.
View StudyDive deeper with our science-backed articles
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