Hericium erinaceus
Nature's Brain Booster
Lion's Mane is a remarkable medicinal mushroom used for centuries in traditional medicine. Modern science has revealed its extraordinary ability to stimulate Nerve Growth Factor (NGF) production—a protein essential for the growth, maintenance, and survival of neurons. This makes it invaluable for supporting cognitive health in aging dogs.

Per Chew
100 mg
Discover how Lion's Mane supports your dog's health and longevity
Contains unique compounds (hericenones and erinacines) that stimulate NGF production, supporting neuron health and regeneration.
Helps maintain memory, learning ability, and mental sharpness, particularly valuable for senior dogs showing cognitive changes.
Provides antioxidant and anti-inflammatory protection for brain cells, helping shield neurons from age-related damage.
Research suggests positive effects on mood and anxiety, promoting calmer, more balanced behavior.
Watch this short animation to understand how Lion's Mane supports your dog's health at the cellular level

Scientific animation showing the mechanism of action of Hericium erinaceus
Lion's Mane contains bioactive compounds called hericenones (found in the fruiting body) and erinacines (found in the mycelium) that can cross the blood-brain barrier. Once in the brain, these compounds stimulate the production of Nerve Growth Factor (NGF), which promotes neuron growth, maintenance, and repair. This is remarkable because NGF itself cannot cross the blood-brain barrier when taken as a supplement.
Timing: Can be given any time of day, with or without food
Effects build over time. Most noticeable cognitive benefits develop after 4-8 weeks of consistent use.
Lion's Mane has been consumed as food and medicine for centuries with an excellent safety record. Studies show it is well-tolerated with no significant adverse effects. It's a natural, whole-food ingredient that provides gentle yet effective cognitive support.
Scientific studies supporting the benefits of Lion's Mane
Mori K, Obara Y, Hirota M, et al.
Biological & Pharmaceutical Bulletin, 2008
Demonstrated that Lion's Mane extracts stimulate NGF synthesis in brain cells.
View StudyMori K, Inatomi S, Ouchi K, et al.
Phytotherapy Research, 2009
Human clinical trial showing improved cognitive function with Lion's Mane supplementation.
View StudyChiu CH, Chyau CC, Chen CC, et al.
International Journal of Molecular Sciences, 2018
Showed Lion's Mane's effects on brain-derived neurotrophic factor and mood-related pathways.
View StudyDive deeper with our science-backed articles
Discover the complete Pawdagen formula