Lion's Mane
Hericium erinaceus
Nature's Brain Booster
Lion's Mane is a remarkable medicinal mushroom used for centuries in traditional medicine. Modern science has revealed its extraordinary ability to stimulate Nerve Growth Factor (NGF) production—a protein essential for the growth, maintenance, and survival of neurons. This makes it invaluable for supporting cognitive health in aging dogs.

Per Chew
100 mg
Key Benefits
Discover how Lion's Mane supports your dog's health and longevity
Nerve Growth Factor Stimulation
Contains unique compounds (hericenones and erinacines) that stimulate NGF production, supporting neuron health and regeneration.
Cognitive Support
Helps maintain memory, learning ability, and mental sharpness, particularly valuable for senior dogs showing cognitive changes.
Neuroprotection
Provides antioxidant and anti-inflammatory protection for brain cells, helping shield neurons from age-related damage.
Mood & Behavior
Research suggests positive effects on mood and anxiety, promoting calmer, more balanced behavior.
See How Lion's Mane Works
Watch this short animation to understand how Lion's Mane supports your dog's health at the cellular level

Scientific animation showing the mechanism of action of Hericium erinaceus
How It Works
Lion's Mane contains bioactive compounds called hericenones (found in the fruiting body) and erinacines (found in the mycelium) that can cross the blood-brain barrier. Once in the brain, these compounds stimulate the production of Nerve Growth Factor (NGF), which promotes neuron growth, maintenance, and repair. This is remarkable because NGF itself cannot cross the blood-brain barrier when taken as a supplement.
Works Best With:
Dosage Information
Timing: Can be given any time of day, with or without food
Effects build over time. Most noticeable cognitive benefits develop after 4-8 weeks of consistent use.
Safety Profile
Lion's Mane has been consumed as food and medicine for centuries with an excellent safety record. Studies show it is well-tolerated with no significant adverse effects. It's a natural, whole-food ingredient that provides gentle yet effective cognitive support.
Research & Citations
Scientific studies supporting the benefits of Lion's Mane
Nerve Growth Factor-Inducing Activity of Hericium erinaceus in 1321N1 Human Astrocytoma Cells
Mori K, Obara Y, Hirota M, et al.
Biological & Pharmaceutical Bulletin, 2008
Demonstrated that Lion's Mane extracts stimulate NGF synthesis in brain cells.
View StudyImproving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment
Mori K, Inatomi S, Ouchi K, et al.
Phytotherapy Research, 2009
Human clinical trial showing improved cognitive function with Lion's Mane supplementation.
View StudyErinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice
Chiu CH, Chyau CC, Chen CC, et al.
International Journal of Molecular Sciences, 2018
Showed Lion's Mane's effects on brain-derived neurotrophic factor and mood-related pathways.
View StudyLearn More About Lion's Mane
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