Brain & Focus

Alpha-GPC

Alpha-Glycerophosphocholine

The Memory Molecule

Alpha-GPC is a highly bioavailable form of choline that efficiently crosses the blood-brain barrier. Once in the brain, it serves as a precursor to acetylcholine, the neurotransmitter most closely associated with memory, learning, and cognitive function. This dual action makes it one of the most effective choline sources for supporting brain health and cognitive performance in dogs.

Most bioavailable form of choline for brain health

Crosses the blood-brain barrier efficiently

Supports acetylcholine production for memory

Also supports cell membrane integrity

Per Chew

25 mg

Key Benefits

Discover how Alpha-GPC supports your dog's health and longevity

Memory Enhancement

Supports acetylcholine production for improved memory formation and recall.

Learning Support

Enhances the ability to learn new commands and retain training through improved neural signaling.

Neuroprotection

Provides phospholipids that support healthy brain cell membranes and neural integrity.

Cognitive Clarity

Supports clear thinking and mental sharpness, especially beneficial for senior dogs.

Watch & Learn

See How Alpha-GPC Works

Watch this short animation to understand how Alpha-GPC supports your dog's health at the cellular level

Click to play

Scientific animation showing the mechanism of action of Alpha-Glycerophosphocholine

How It Works

After ingestion, Alpha-GPC is rapidly absorbed and crosses the blood-brain barrier. In the brain, it is metabolized to release choline, which combines with acetyl-CoA to form acetylcholine. This neurotransmitter is essential for memory formation, learning, and muscle control. Alpha-GPC also contributes to phosphatidylcholine synthesis, supporting neuronal membrane structure and function. The result is enhanced neural communication and improved cognitive performance.

Works Best With:

L-Tyrosine

Lion's Mane

Phosphatidylserine

Dosage Information

Per Chew25 mg

Small Dogs (<25 lbs)25 mg (1 chew)

Medium Dogs (25-50 lbs)50 mg (2 chews)

Large Dogs (>50 lbs)75 mg (3 chews)

Timing: Best given in the morning with food

Highly bioavailable; lower doses are effective compared to other choline sources.

Safety Profile

Alpha-GPC is well-tolerated in dogs with an excellent safety profile. May cause mild GI upset in sensitive individuals. Consult your veterinarian before use.