Phosphatidylserine: The Brain Cell Builder
Phosphatidylserine (PS) is a critical phospholipid that forms the structural foundation of brain cell membranes, supporting cognitive function and memory in aging dogs.
Why does my dog's memory fade?
Brain cell membranes are made primarily of phospholipids, including phosphatidylserine. As dogs age, PS levels decline, reducing membrane fluidity and impairing neurotransmitter communication.
This affects:
- Memory FormationReduced synaptic plasticity impairs learning
- Signal TransmissionSlower neurotransmitter release affects cognition
- Cellular IntegrityCompromised membrane structure accelerates aging
Memory Performance by Age
With and without Phosphatidylserine supplementation
*Based on canine cognitive function studies
Rebuilding Brain Cell Membranes
Phosphatidylserine supplementation restores brain cell membrane fluidity, enhancing neurotransmitter communication and supporting memory, learning, and cognitive aging.
Membrane Restoration
PS directly incorporates into brain cell membranes, restoring fluidity and structural integrity for optimal neurotransmitter function.
Synaptic Enhancement
Improves synaptic plasticity—the brain's ability to form new connections—essential for learning and memory formation in aging dogs.
Cognitive Support
Supports learning ability, memory retention, and mental clarity—helping senior dogs maintain cognitive function and engagement.
How Phosphatidylserine Works
Membrane Integration
Phosphatidylserine is one of the primary phospholipids in the neuronal membrane bilayer. When supplemented, PS is incorporated into brain cell membranes, restoring fluidity and enabling proper neurotransmitter release and receptor function.
Apoptosis Regulation
PS helps regulate programmed cell death (apoptosis), preventing premature neuronal loss. This is particularly important in aging brains where excessive apoptosis contributes to cognitive decline.
Neurotransmitter Support
By improving membrane fluidity, PS enhances the function of neurotransmitter systems (acetylcholine, dopamine, serotonin), which are critical for learning, memory, mood, and cognitive performance.
Backed by Research
Safety Profile
Rapidly Brain-Bioavailable Phospholipid
- ✓Naturally occurring phospholipid with rapid absorption and excellent brain bioavailability
- ✓Reaches high concentrations in brain tissue where it supports neuronal health
- ✓Well-tolerated with minimal reported side effects in animal studies
- ✓Supports natural stress response and emotional balance in dogs
- ✓Safe for long-term supplementation in anxious and aging dogs
- ✓Naturally supports cognitive function and memory in senior dogs
- ✓Compatible with other brain-supporting and stress-management ingredients
All Pawdagen ingredients are selected for safety, efficacy, and compatibility with your dog's health.
Synergistic Ingredients
PS + Ginkgo Biloba
Enhanced cognitive support. Ginkgo's circulation benefits combine with PS's membrane support for comprehensive brain health.
PS + Lion's Mane
Brain cell regeneration. Lion's Mane stimulates NGF while PS provides structural support for optimal neuroplasticity.
PS + Alpha-GPC
Memory enhancement. Both support acetylcholine synthesis and membrane health for superior learning and recall.
PS + Bacopa
Cognitive resilience. Combines membrane support with nervous system nourishment for comprehensive brain aging support.