Lion's Mane: The Brain Builder
A functional mushroom powerhouse that stimulates Nerve Growth Factor (NGF) to support memory, focus, and cognitive longevity in aging dogs.
Why does my dog's mind slow down?
Cognitive decline in dogs stems from the loss of neurons and reduced neuroplasticity. As dogs age, their brain's ability to form new connections weakens, leading to memory loss, confusion, and reduced mental sharpness.
This manifests as:
- Memory LossForgetting familiar people, places, or commands
- Reduced Mental EngagementLess interest in play, training, or problem-solving
- Neuronal LossNeurons die faster than they can be replaced
NGF Stimulation by Lion's Mane
Relative increase in Nerve Growth Factor synthesis
*Based on in vitro studies demonstrating NGF synthesis stimulation by Hericium erinaceus extract
Rebuilding the Neural Network
Lion's Mane contains unique compounds—hericenones and erinacines—that cross the blood-brain barrier and stimulate Nerve Growth Factor (NGF), the molecule responsible for neuron growth and survival.
NGF Stimulation
Lion's Mane directly stimulates the production of Nerve Growth Factor, the essential protein that supports neuron survival and growth.
Neuroplasticity
Supports the brain's ability to form new neural connections, enabling your dog to learn, remember, and adapt throughout their life.
Cognitive Vitality
Helps restore mental sharpness, memory, and the joy of learning—keeping your dog mentally engaged and present.
How Lion's Mane Works
NGF Synthesis Stimulation
Hericenones and erinacines in Lion's Mane cross the blood-brain barrier and directly stimulate NGF production in the brain. NGF is the primary growth factor responsible for neuron survival, growth, and differentiation.
Neuroplasticity Enhancement
By supporting NGF, Lion's Mane enhances the brain's ability to form new synaptic connections. This is critical for learning, memory formation, and maintaining cognitive function as dogs age.
Myelin Sheath Protection
NGF supports the maintenance of myelin, the protective coating around nerve fibers. Healthy myelin ensures faster neural signaling and better cognitive function.
Anti-inflammatory Support
Lion's Mane contains compounds that help reduce neuroinflammation, a key driver of cognitive decline. By reducing brain inflammation, it creates an environment where neurons can thrive.
Backed by Research
Safety Profile
Edible Fungal Extract with Excellent Tolerability
- ✓Edible fungal extract with excellent safety profile—non-toxic and well-tolerated by dogs
- ✓Supports natural nerve growth factor (NGF) production for brain health
- ✓Most dogs tolerate it exceptionally well with minimal adjustment period
- ✓Safe for long-term daily use without tolerance or dependency concerns
- ✓Naturally supports cognitive function and neuroplasticity in aging dogs
- ✓Compatible with other cognitive and longevity ingredients
- ✓Ideal for senior dogs experiencing age-related cognitive changes
All Pawdagen ingredients are selected for safety, efficacy, and compatibility with your dog's health.
Synergistic Ingredients
Lion's Mane + Phosphatidylserine
Brain cell health synergy. PS supports brain cell membrane integrity while Lion's Mane stimulates NGF for comprehensive cognitive support.
Lion's Mane + Alpha-GPC
Memory powerhouse. Both support acetylcholine production and brain cell health for enhanced learning and memory retention.
Lion's Mane + Bacopa
Cognitive resilience. Both support neuroplasticity and cognitive function while protecting against age-related mental decline.
Lion's Mane + Ginkgo Biloba
Brain circulation and growth. Ginkgo improves blood flow while Lion's Mane stimulates NGF for optimal cognitive vitality.