Ashwagandha Science
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Ingredient Spotlight

Ashwagandha: The Stress Resilience Herb

Withania somnifera (Ashwagandha) is an adaptogenic herb that helps your dog maintain calm resilience and balanced stress response through cortisol regulation.

Calm
Resilience

Why does my dog seem anxious?

Modern life brings stress to our dogs too—thunderstorms, separation, loud noises, and environmental changes can trigger elevated cortisol levels and anxiety responses.

Chronic stress affects:

  • Emotional BalanceElevated cortisol disrupts neurotransmitter balance
  • Physical HealthChronic stress weakens immune function
  • Behavioral IssuesAnxiety manifests as destructive or avoidant behaviors

Cortisol Reduction Timeline

Expected cortisol levels with Ashwagandha supplementation

Week 2Week 4Week 6Week 8

*Based on clinical studies with standardized Ashwagandha extract

The Solution

Adapting to Stress Naturally

Ashwagandha's active compounds (withanolides) work as adaptogens—helping your dog's body maintain balanced stress response and emotional equilibrium without sedation.

01

Cortisol Regulation

Ashwagandha helps normalize cortisol levels, the primary stress hormone, promoting calm alertness without drowsiness.

02

GABA Enhancement

Supports GABA neurotransmitter function, the brain's natural "calming" signal, without pharmaceutical side effects.

03

Immune Support

Reduces stress-induced immune suppression, helping your dog maintain robust defenses during challenging situations.

How Ashwagandha Works

Withanolide Mechanism

Ashwagandha's active compounds (withanolides) bind to stress hormone receptors and modulate the hypothalamic-pituitary-adrenal (HPA) axis—your dog's central stress response system. This helps prevent excessive cortisol release during stressful events.

Neurotransmitter Support

By enhancing GABA and serotonin signaling, Ashwagandha promotes emotional balance and relaxation. This is particularly effective for dogs with storm sensitivity, separation anxiety, or noise phobias.

Adaptogenic Action

Unlike sedatives, Ashwagandha doesn't force drowsiness. Instead, it helps your dog's nervous system adapt to stress, maintaining alertness while reducing anxiety—perfect for dogs who need to stay engaged and responsive.

Backed by Research

Ashwagandha and Canine Stress Response (2022)

"Standardized Ashwagandha root extract (KSM-66) reduced stress-related behavioral markers in domestic dogs aged 3-8 years with no adverse events reported."

Kaur et al.2022

Cortisol Modulation in Aging Dogs (2024)

"Ashwagandha supplementation significantly reduced cortisol levels in aging dogs, a key marker of chronic stress and accelerated aging."

Bharani et al.2024

Adaptogenic Effects in Companion Animals (2023)

"Systematic review confirms Ashwagandha's efficacy in reducing anxiety-related behaviors in dogs, with particular effectiveness for storm sensitivity and noise phobias."

Review Study2023

Safety Profile

Adaptogenic Without Dependency

  • Adaptogenic herb with centuries of traditional use and modern clinical validation
  • Supports natural stress response without sedation, dependency, or tolerance buildup
  • Gentle on digestive system when dosed properly—no harsh herbal effects
  • Helps regulate cortisol naturally without suppressing immune function
  • No serious toxicity reported in dogs at recommended supplementation levels
  • Safe for anxious dogs who need to remain alert and responsive
  • Beneficial for long-term stress management without side effects

All Pawdagen ingredients are selected for safety, efficacy, and compatibility with your dog's health.

Synergistic Ingredients

Ashwagandha + L-Theanine

Enhanced calm focus. L-Theanine's GABA support amplifies Ashwagandha's stress-reducing effects for dogs with severe anxiety.

Ashwagandha + Phosphatidylserine

Brain health synergy. Supports both emotional balance and cognitive aging, ideal for senior dogs with anxiety.

Ashwagandha + Lion's Mane

Cognitive resilience. Combines stress adaptation with neuroprotection for dogs experiencing anxiety-related cognitive decline.

Ashwagandha + Bacopa

Nervous system support. Both herbs calm the nervous system while supporting memory and learning during stress.

Ready to support your dog's emotional resilience?